After rigorously screening and processing genes, we have identified multiple shared genes exposed in the immune response of COVID-19 with COPD conditions (including CCL2, MMP9, IL1A, LEP, SERPINE1, CXCL10, EGF, CCL4, STAT1, and HIF1A). The gene discussed is CXCL10; the disease is chronic obstructive pulmonary disease.