In addition, there was no significant change in the level of A2AR in the cordycepin group after GCI, which seemed to contradict the previous report that the level of A2AR increases accompanied with the supplement of exogenous adenosine in the hippocampal CA1 area after temporary cerebral ischemia (Seydyousefi et al., 2019). This evidence concerns the gene ADORA2A and Cerebral ischemia.