SQSTM1 and amyotrophic lateral sclerosis: MSP has also been linked to mutations in other ALS-associated genes, namely HNRNPA1 and HNRNPA2B1 (Kim et al., 2013), SQSTM1 (Bucelli et al., 2015), and a novel missense variant of Annexin A11 (ANXA11) (Leoni et al., 2021).