This is supported by the existence of similar mutations in hnRNPA1, hnRNPA2B1, SQSTM1 that are also associated with TDP-43 inclusions and ALS, FTD, IBM, and PBD (Kim et al., 2013; Bucelli et al., 2015). Here, HNRNPA2B1 is linked to amyotrophic lateral sclerosis.