Downregulated DEGs were in pathways in cancer, prostate cancer, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, viral protein interaction with cytokine and cytokine receptor, focal adhesion, Th17 cell differentiation, TNF signaling pathway, FoxO signaling pathway, and inflammatory bowel disease (Figure 3(b)). This evidence concerns the gene TNF and prostate cancer.