DYNC1I1, the binding subunit of cytoplasmic dynein, could assist the cytoplasmic dynein-mediated transport of P65 to the nucleus, following which P65 could promote the expression of IL-6 and activate the STAT3 phosphorylation to promote the proliferation and metastasis of gastric cancer cells 30. The gene discussed is DYNC1I1; the disease is gastric cancer.