Recently, another type of condensates formed by LLPS − RNA and protein (RNP) granules, such as SGs − has received much attention due to its linkage to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (Patel et al., 2015; Alberti and Hyman, 2016). Here, RNPC3 is linked to amyotrophic lateral sclerosis.