CDKN2A and pancreatic neoplasm: Surveillance of high-risk individuals (HRIs), such as people with a pathogenic germline variant in a pancreatic cancer susceptibility gene, for example, ATM, BRCA1, BRCA2, CDKN2A, CPA1, CPB1, MLH1, MSH2, MSH6, PALB2, PMS2, PRSS1, and STK11, has the potential to reduce mortality through detection of early, potentially curable, PDAC and its precursor lesions (Canto et al., 2018; Vasen et al., 2016).