CD40LG and systemic lupus erythematosus: By detecting the level of serum anti-dsDNA antibody and urinary protein in mice, and observing the pathological changes in SLE mouse kidneys, we further clarified that interfering with the expression of CD40L in SLE mice significantly reduced the level of serum anti-dsDNA antibody (Figure 1(d)) and urinary protein in mice (Figure 1(e)).