IL1B and osteoarthritis: Previous studies used rat chondrocytes pretreated with Achyranthes bidentate Blume at 3-μg/mL, 10-μg/mL, and 30-μg/mL, and subsequently stimulated with IL-1β (10-ng/mL) and discovered that Achyranthes bidentate Blume might be a potential drug for treating osteoarthritis [35].