Alterations in other proteins involved in triad formation and maintenance, including caveolin-3 (CAV3), amphiphysin-1 (BIN1), dysferlin (DYSF), myotubularin (MTM1), and striated muscle preferentially expressed protein kinase (SPEG), have also been linked to skeletal myopathy phenotypes in patients and rodent models (118, 132, 229). Here, MTM1 is linked to Skeletal myopathy.