Other endocrine complications are usually transient, such as diabetes insipidus in 16.5% (7–28%), inappropriate antidiuretic hormone (ADH) secretion in 9% (5–14%), hypopituitarism in 2% (1–4%), namely central hypoadrenalism in 1–2%, central hypogonadism in 3–6%, and central hypothyroidism in 1–6%. This evidence concerns the gene AVP and hypopituitarism.