The two most significant dmCpGs were cg01469688 in the promoter of the Suppressor Of Cancer Cell Invasion (SCAI) gene (FDR = 0.004), and cg06952751 in the promoter of the C18orf8 gene (FDR = 0.004), with a 0.1 mmol/l increase in LDL-Cholesterol associated with a 1.3% and 3.8% increase in methylation of cg01469688 and cg06952751, respectively (cg01469688: 95% CI = 0.09, 0.18; cg06952751: 95% CI = 0.25, 0.52). This evidence concerns the gene RMC1 and cancer.