Total plasma ghrelin levels did not change significantly from before to 48 weeks after eradication (F4 = 0.885, p = .48), but there was a significant difference in total plasma ghrelin levels between open-type and closed-type atrophic gastritis (F1 = 10.193, p < .01) (Figure 1(A)). Here, GHRL is linked to chronic atrophic gastritis.