GHRL and chronic atrophic gastritis: Similarly, acyl plasma ghrelin levels showed no significant change from before to 48 weeks after eradication (F4 = 0.212, p = .93), but there was a significant difference in acyl plasma ghrelin levels between open-type and closed-type atrophic gastritis (F1 = 7.844, p = .01) (Figure 1(B)).