Tfh (CD4+CXCR5+PD-1+Tfh, CD4+CD44+CXCR5+PD-1+Tfh), B (GC B (B220+GL7 +), PC (B22010 CD138 +)) cells, which are associated with high concentrations of autoimmune antibodies and LN, are decreased in animal model after MSCT. The gene discussed is CXCR5; the disease is lobular neoplasia.