Further adjustment for CRP, non-HDL cholesterol, HbA1c, adiponectin and eGFR did not substantially alter the estimates (Table 2, Model 2), however, the adjustment for triglycerides and HDL-cholesterol slightly attenuated the results to 0.88 (0.75; 1.02) for any diabetes complications, 0.85 (0.72; 1.01) for microvascular and 0.95 (0.67; 1.34) for macrovascular complications. The gene discussed is CRP; the disease is diabetes mellitus.