Moreover, MALT1 induces the differentiation of T‐helper (Th) 1 and Th17 cells, which further aggravates many inflammatory and autoimmune diseases, such as psoriasis, rheumatoid arthritis, etc.17, 18, 19Besides, as mentioned above, IBD is a chronic inflammatory disease, which is characterized by abnormal intestinal immune response.4 The gene discussed is MALT1; the disease is inflammatory bowel disease.