The only study dealing with esophageal adenocarcinoma, including 74 patients with type II/III adenocarcinoma of the esophagogastric junction (AEG) (Huang et al. 2015), also found a significantly higher rate of CD147 expression in EAC compared to non-malignant esophageal tissue. This evidence concerns the gene BSG and esophageal adenocarcinoma.