CD147 immunostaining was detectable in weak intensities in 11.7%, moderate intensities in 41.7%, and strong intensities in 46.7% of EACs, while CD147 immunostaining was weak in 14.2%, moderate in 50.5%, and strong in 35.3% of ESCC specimens. The gene discussed is BSG; the disease is esophageal squamous cell carcinoma.