Several studies have addressed elevated expression levels of GPR34 in malignancies, including cervical cancer [7], metastatic melanoma [6], MALT lymphoma [1, 2], BCR/ABL-positive leukemia [9], gastric cancer [5, 8], and colon cancer [4], as well as its essential roles in tumor development and progression. The gene discussed is GPR34; the disease is malignant colon neoplasm.