Firstly, the levels of ALDOA expression in 53 colorectal cancer tissues were significantly higher than that in 28 non-tumor colorectal tissues in GSE6988 dataset (p < 0.05, Fig. S5C) and higher ALDOA expression was associated significantly with a shorter OS of 177 colon cancer patients in GSE17538 dataset (p = 0.008, Fig. S5D). Here, ALDOA is linked to malignant colon neoplasm.