It was found that the expression levels of CDH11, SPARC, FN1, and FSTL1 genes in unruptured aneurysms were higher than those in healthy samples, while the expression levels of WNT11, PCDH9, and GPC3 in unruptured aneurysms were lower than those in healthy samples (Fig. 6A–G). This evidence concerns the gene SPARC and aneurysm.