Bexarotene also significantly (p < 0.05) increased the time to initial tumor development in MMTV-neu mice (Fig. 3B) but was not as effective as V-125, delaying tumor development by only 4 weeks (35.9 ± 4.2 weeks vs. control 31.7 ± 4.1 weeks). The gene discussed is ERBB2; the disease is neoplasm.