To examine the role of FA core-complex defect in the emergence of the FA-tumor specific differentially-expressed pathways, the global mRNA expression profiles, as obtained via genome-wide RNA sequencing, of the FANCA-deficient, FA-HNSCC cell line VU1365-T carrying an empty vector plasmid (VU1365 + EV) were compared to its FANCA-gene corrected counterpart VU1365 + FANCA (Supplementary Excel File 7). This evidence concerns the gene FANCA and neoplasm.