The protein quantification in relation to vinculin and normalized to 11q22.2 silent FA-HNSCC sample VU1131-T indicated higher protein expression of YAP1 and BIRC3 in all 11q22.2 amplified FA-HNSCCs compare to the 11q22.2 silent and normal cell lines (Fig. 5b). The gene discussed is YAP1; the disease is Friedreich ataxia.