DTNBP1 and cancer: Additionally, DNA methylation levels of DTNBP1 promoter were considered for the diagnosis of schizophrenic individuals12, which partially suggested that DTNBP1 might be regulated in the liver via methylation processes.Accumulating evidence suggests that DTNBP1 functions in cancer, suggesting that it may regulate and interact with all three D-type cyclins (cyclin D1, D2, and D3) and affect cell cycle progression4.