It is reported that CPS1, IGFBP3, MCM5, MCM7, NT5E, PLK1, PTTG1, SERPINB5, TXNRD1 and TYMS were associated with the prognosis of lung adenocarcinoma or non-small cell lung cancer, which was also included in our 14 genetic findings27–36. The gene discussed is IGFBP3; the disease is lung adenocarcinoma.