As shown in Table 2, Univariate analysis showed that ENKTL patients with higher levels of PD-L1 in tumor tissues (P = 0.0218) were more difficult to achieve CR, as were patients with high levels of LDH (P = 0.0222), Ki-67 index (P = 0.0304) and EBV-DNA copies (P = 0.0087). The gene discussed is CD274; the disease is neoplasm.