CD274 and neoplasm: In addition, Chen BJ, Chapuy B and other scholars have found that PD-L1 is expressed in HL, DLBCL, ENKTL and other lymphoma tissues, but no expression has been detected in Burkitt lymphoma17, similar to this, this study is also found that PD-L1 is highly expressed in tumor tissues of ENKTL and DLBCL patients, it is suggested that the increased expression of PD-L1 is one of the possible reasons for the defect of cellular immune function in patients.