Since RNA-sequence analysis suggests ZFP64 might involve in the inflammatory response and innate immune response, and GAL-1 functions as a negative regulator of innate immune cells, including T cell activation and survival, and results in immune evasion of tumor cells [24], we screened the impact of tumors with high level of ZFP64 on the tumor immune microenvironment in the humanized NSG mice by CyTOF. Here, LGALS1 is linked to neoplasm.