Univariate analysis showed that age, baseline CA199 level, CEA level, albumin level, peripancreatic invasion, degree of weight loss, NLR, operative procedure, lymph node metastasis, hepatic metastasis, the number of distant organ metastasis and postoperative adjuvant chemotherapy were the relevant factors affecting the prognosis of PHC subgroup (P<0.05). The gene discussed is ALB; the disease is metastatic malignant neoplasm in the lymph nodes.