Similarly, Liu and colleagues ascertained that circ_MACF1 sponged miR-544a to suppress NSCLC progression by post-transcriptionally regulating the expression of FBXW7 [15], wherein FBXW7 plays an important role in gefitibin resistance in NSCLC [44]. The gene discussed is FBXW7; the disease is non-small cell lung carcinoma.