Pathway enrichment analysis revealed the involvement of miR‐497‐5p in cancer‐related pathways including proteoglycans in cancer (hsa05205|p = 1.45e‐11), hippo signaling pathway (hsa04390|p = 1.11e‐6), mTOR signaling pathway (hsa04150|p = 2.69e‐4), TGF‐beta signaling pathway (hsa04350|p = 7.64e‐4), and p53 signaling pathway (hsa00310|p = 8.27e‐4). The gene discussed is TGFB1; the disease is cancer.