Based on inhibitory effects of broussonin A and B on angiogenic responses, we next examined the ability of broussonin A and B to regulate proliferation and invasion in NSCLC p53 wild‐type A549 and p53‐deficient H1299 cells as well as ovarian cancer p53‐deficient SKOV‐3 cells (Figure 7). The gene discussed is TP53; the disease is ovarian cancer.