Although the inhibitory potency of broussonin A and B in regulating cancer cell proliferation and invasion appears to be dependent on the specific cell/tissue types or p53 expression status, these findings suggest anti‐tumour activities of broussonin A and B in NSCLC and ovarian cancer cells might be correlated with suppression of integrin β1 expression. Here, TP53 is linked to non-small cell lung carcinoma.