CD4 and progressive multifocal leukoencephalopathy: Often this was accompanied by immunosuppressive therapy, but several case reports of PML in untreated sarcoidosis patients can be found.5,7,8 It was also shown that the CD4+ T cell count was reduced in these patients.5,8 In our cohort, four from six PML patients with sarcoidosis were not under immunosuppressive therapy at the time of developing first PML symptoms.