In another study of 150 patients, up to 30% with the mutation PLN (phospholamban) p.Arg14del had LGE on CMR with a normal LVEF, suggesting this to be an early feature and higher risk of arrhythmias in carriers of this mutation, but also attesting to the phenotypic insights CMR offers for those with underlying genetic substrate (33). Here, PLN is linked to cardiac arrhythmia.