Vice versa, hyperactivating mTORC1 signaling via TSC2 knockout as previously described (Deng et al., 2021) enhanced the number of CD31-positive vascular endothelial cells induced by LL37.These results suggested mTORC1 acted as an regulator of LL37-induced angiogenesis in rosacea. Here, PECAM1 is linked to rosacea.