ELMO1 and infection: Consistent with previous studies about the ELMO1 participated in regulating cell migration in mice and cell culture (Gumienny et al., 2001; Grimsley et al., 2004; Arandjelovic et al., 2019), we found that the random ameboid migration of neutrophils and T-cells were significantly reduced in elmo1−/− larvae, and the chemotaxis of neutrophils was also reduced after injury or infection in elmo1−/− larvae by in vivo live imaging (Figure 2, Figure3).