Exploratory studies on the genetic or histological homogeneity of HT and PTC have found that the common BRAF-V600E mutation in PTC is related to HT (6) where the expression of BRAF protein in HT tissue is 2.2 times higher than that in normal thyroid tissue (7), in addition to being related to tumor size, extraglandular invasion, and pathological type. The gene discussed is BRAF; the disease is neoplasm.