BRAF and neoplasm: A few exploratory studies on the genetic or histological homogeneity of HT and PTC have suggested that BRAF-V600E mutation, which is very common in PTC, is not only related to tumor size, extraglandular invasion, and pathological type, but also HT (6), where the expression of BRAF protein was 2.2 times higher than that in normal thyroid tissue (7).