FOXE1 and autoimmune thyroid disease: 1) Thyroid specific gene: TSHR is a thyroid hormone receptor, which is highly related to autoimmune thyroid diseases; FOXE1 participates in thyroid morphogenesis, binds to the promoter region of thyroglobulin and thyroid peroxidase, and participates in the expression of thyroglobulin and thyroid peroxidase.