We found that the expression of PD-L1 was correlated with serum albumin (P < 0.05) and pathological type (P < 0.05) and had a negative correlation with EGFR mutation but did not correlate with gender, age, smoking status, combined with underlying diseases, tumor stage, whether it was initially treated or not, sampling site, specimen type, specimen storage time, R-IFN, CD4, CD8, NLR, CRP, and LDH. Here, IFNA1 is linked to neoplasm.