What's more, 5 of the first 20 enriched KEGG pathways are related to PI3K-Akt signaling pathway, Epstein-Barr virus infection, Kaposi sarcoma-associated herpesvirus infection, proteoglycans in cancer, and EGFR tyrosine kinase inhibitor resistance. The gene discussed is EGFR; the disease is Epstein-Barr virus infection.