ERAP2 expression was significantly positively correlated to the infiltration levels (CD8+ T cells, p=4.09e-03; M0 macrophages, p=1.93e-02; regulatory T cells, p=2.29e-02; M1 macrophages, p=2.16e-08; activated NK cells, p=1.00e-04; M2 macrophages, p=1.24e-06), consistent with previous findings in our study, further suggesting that ERAP2 may act as a tumor suppressor in SqCLC in an immune-promoting manner. This evidence concerns the gene CD8A and neoplasm.