M2 macrophages (CD136+MRC1+C1QA+C1QB+, P=0.007) and mast cells (TPSAB1, P=0.007) were decreased in early-onset preeclampsia samples, while M1 macrophages (CD86+MSR1+) were not altered based on gene expression (Figures 4A–C). This evidence concerns the gene MRC1 and preeclampsia.