IL27 and clostridium difficile infection: IL-27, produced by antigen presenting cells after stimulation with toll like receptor (TLR) ligands or infectious agents (Cao et al., 2014), can stimulate human cathelicidin antimicrobial peptide (LL-37) production in human colonic epithelial cells (both in vitro and in vivo, CDI patient blood and feces IL-27 levels positively correlate with LL-37 levels).