Various angiogenic factors, such as VEGFA and FGF2, were shown to play a central role in the post-stroke vascular reconstruction.25 Suppression of FSAP at early stage robustly increased levels of VEGFA, FGF2, and their receptors VEGFR2 and FGFR1 in the mouse brain after stroke. This evidence concerns the gene FGF2 and stroke disorder.