More specifically, variants in the KRT74 and KRT85 genes are associated with ectodermal dysplasia; KRT25 and KRT74 variants are associated with woolly hair; KRT75 variants are associated with pseudo-folliculitis barbae; KRT81, KRT83 and KRT86 variants are associated with monilethrix; KRT17 variants are associated with anonychia congenita; and variations in KRT25, KRT71 and KRT74 are associated with hypotrichosis (Table 1). This evidence concerns the gene KRT25 and nonsyndromic congenital nail disorder 4.