These SA-enriched and STn- or PSA-coated tp53 mutant cells may be pro-inflammatory, as shown in IBD patient samples [80], and acquire advantages for cancer progression due to increased proliferation, genomic instability, and metastatic activity via STAT3 and NF-κB signaling [40, 78, 81]. The gene discussed is NFKB1; the disease is inflammatory bowel disease.