For example, long non-coding metastasis-associated lung adenocarcinoma transcript 1 (lnc-MALAT1) and micro RNA (miR)-125a were increased in sepsis patients compared with healthy controls and positively correlated with APACHE-II score, SOFA score, serum creatinine, CRP, TNF-α, IL-1β, IL-6, and IL-8. This evidence concerns the gene IL1B and Sepsis.