HLA-B and toxic epidermal necrolysis: They are also used in genetic screening e.g. HLA-B*57:01 in Caucasian population for abacavir hypersensitivity, HLA-B*15:02 in Chinese and Asians for carbamazepine induced life-threatening conditions like Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) [9, 29].