Indeed, in type III EMT, tumor cells have been shown to present a loss of expression of adhesion proteins [6], to secrete various metalloproteases, such as MMP9 or ADAM19 [7], leading to the digestion of the extracellular matrix and then to the escape of the primary tumor and the migration through the blood or lymphatic circulation [4,5]. The gene discussed is ADAM19; the disease is neoplasm.