Among these miRNAs, miR-101 was the most frequently observed, since it has been described to target EZH2 in gastric cancer cell lines (BGC-823, SGC-7901, AGS, and MKN-45), in head and neck squamous cell carcinomas (HNSCCs) and in the glioblastoma cell line U87. This evidence concerns the gene EZH2 and head and neck squamous cell carcinoma.