ADIPOQ and type 2 diabetes mellitus: While this generated an improvement in performance (vs T2DM AUC = 0.96 [CI: 0.91-1.00], vs NOD AUC = 0.93 [CI: 0.86-1.00] compared to 0.90 and 0.91 respectively), both adiponectin (vs T2DM OR = 1.27, CI: 1.05-1.71; vs NOD 1.31, CI: 1.03-1.93) and IL-1Ra (vs T2DM OR = 1.03, CI: 1.01-1.05; vs NOD OR = 1.03, CI: 1.01-1.06) retained their association with T3cDM.