Surveying clinical literature that is typically beyond the biogerontological purview, he notes that many senescent pathologies and conditions are linked to mTOR over-activity, including cancer, atherosclerosis, hypertension, type 2 diabetes, osteoporosis, osteoarthritis, macular degeneration, and Alzheimer’s and Parkinson’s diseases (Blagosklonny, 2006a; Tsang et al., 2007). The gene discussed is MTOR; the disease is osteoporosis.