In contrast to CRP and IL-6, which are affected by acute fluctuations in inflammation levels, for example due to infections (Hunter and Jones, 2015, Rhodes et al., 2011), suPAR is an emerging marker of systemic chronic inflammation that is less affected by acute changes and short-term influences (Rasmussen et al., 2021a, Rasmussen et al., 2021b). Here, CRP is linked to infection.