Of the biomarkers that significantly associated with MR-proADM, leptin, chemerin, and IL-22 neither associated (p > 0.05) with all-cause mortality in the simple model (model 2; adjusted for sex, age, and BMI) nor in the fully adjusted model (model 4; adjusted for sex, age, BMI, arterial hypertension, diabetes, eGFR, HDL, smoking, and physical activity). The gene discussed is LEP; the disease is Hypertension.